Fluorouracil impurity B (Y0000763) is a EP Standard of Fluorouracil with CAS Registry No: 496-76-4
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CAT No. CS-EG-02991
Category EP Standards
Parent API Fluorouracil
CAS 496-76-4
Mol. Weight 128.09 g/mol
Mol. Formula C4H4N2O3

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More info about Fluorouracil impurity B (Y0000763)
Synonyms dihydropyrimidine-2,4,5(3H)-trione;5-Hydroxy Uracil; isobarbituric acid
Appearance White to Off-White Solid
Application Notes Studies show that it can form stable base pairs with all four bases in a DNA duplex. It has been used as oxidative DNA damage biomarker in tissue engineered skin
References Varatharasa T. et al.:chem.comm., 3, 400 (2005); Jaruga, P. et al.: Nclec cid Res., 24, 1389 (1996); Rodriguez, H. et al.: Adv. Exp. Med. Biol., 534, 129 (2003);
Smiles O=C1NC(C(CN1)=O)=O
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy

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