Abacavir Triphosphate TEA Salt is a Metabolite of Abacavir with CAS Registry No: 137820-58-7 (free acid)
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CAT No. CS-T-93744
Category Metabolites
Parent API Abacavir
CAS 137820-58-7 (free acid)
Mol. Weight 624.46 g/mol
Mol. Formula C20H36N7O10P3

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More info about Abacavir Triphosphate TEA Salt
Synonyms triethylamine ((1S,4R)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methyl triphosphate; Abacavir Triphosphate triethylammonium Salt
Application Notes Abacavir Triphosphate TEA Salt, is a metabolite of Abacavir. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.
The balance used are calibrated with weights Traceable to National Standards NIST for accuracy

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